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Endoscopy · CPT 45378

Colonoscopy (diagnostic) costs $28 to $31,686 cash at US hospitals.

938 hospitals publish a cash price for CPT 45378. The median is $1,469, and the most expensive hospital lists 1138× the cheapest. Below, the same comparison by metro area.

938 US hospitals list a cash price for colonoscopy (diagnostic) (CPT 45378) in their price transparency files. The lowest is $28, the median $1,469 and the highest $31,686. That is a spread of 1138 times for the same billing code.

1428 hospitals also publish negotiated insurer rates for it, with a median of $422; the median list price (gross charge) is $2,778.

Comparisons are published for 69 metro areas with at least three hospitals listing a cash price. The lowest metro median is $224 in Fort Wayne, IN; the highest is $6,651 in Birmingham, AL.

$28
lowest cash price in the US
$1,469
median cash price
$422
median negotiated rate (1,428 hospitals)
$2,778
median list price (gross charge)

Colonoscopy (diagnostic) near you

Every hospital within your radius that lists a price, sorted by price with the distance.

By metro area

lowest · median · highest cash price

New York, NY-NJ

39 hospitals

$352

Los Angeles, CA

28 hospitals

$268

Dallas, TX

26 hospitals

$929

Philadelphia, PA-NJ-DE-MD

15 hospitals

$452

Riverside, CA

15 hospitals

$592

Chicago, IL-IN

15 hospitals

$301

Portland, OR-WA

14 hospitals

$616

San Francisco, CA

12 hospitals

$2,080

Detroit, MI

12 hospitals

$238

Cleveland, OH

12 hospitals

$508

Houston, TX

11 hospitals

$291

Columbus, OH

11 hospitals

$457

Cincinnati, OH-KY-IN

10 hospitals

$1,850

Minneapolis, MN-WI

9 hospitals

$31

Pittsburgh, PA

9 hospitals

$609

Kansas City, MO-KS

8 hospitals

$392

Atlanta, GA

8 hospitals

$1,670

Boston, MA-NH

8 hospitals

$609

Washington, DC-VA-MD-WV

8 hospitals

$1,444

Miami, FL

8 hospitals

$385

Lafayette, LA

7 hospitals

$271

Seattle, WA

7 hospitals

$1,423

Providence, RI-MA

6 hospitals

$596

Orlando, FL

6 hospitals

$2,483

St. Louis, MO-IL

6 hospitals

$820

Omaha, NE-IA

5 hospitals

$368

Sacramento, CA

5 hospitals

$2,322

San Diego, CA

5 hospitals

$749

Duluth, MN-WI

5 hospitals

$1,775

Boise City, ID

5 hospitals

$739

Fort Wayne, IN

5 hospitals

$199

Birmingham, AL

5 hospitals

$441

Indianapolis, IN

5 hospitals

$277

Jackson, MS

5 hospitals

$832

Rochester, NY

4 hospitals

$434

Joplin, MO-KS

4 hospitals

$827

Richmond, VA

4 hospitals

$3,969

Charleston, SC

4 hospitals

$5,910

New Orleans, LA

4 hospitals

$484

Davenport, IA-IL

4 hospitals

$516

Denver, CO

4 hospitals

$622

Harrisburg, PA

4 hospitals

$443

Des Moines, IA

4 hospitals

$628

Nashville, TN

4 hospitals

$1,163

Memphis, TN-MS-AR

3 hospitals

$948

Wichita, KS

3 hospitals

$575

Williamsport, PA

3 hospitals

$510

Worcester, MA

3 hospitals

$2,961

Cape Coral, FL

3 hospitals

$1,040

Santa Rosa, CA

3 hospitals

$641

Seaford, DE

3 hospitals

$1,200

Buffalo, NY

3 hospitals

$245

Eureka, CA

3 hospitals

$268

Baton Rouge, LA

3 hospitals

$932

Hilo, HI

3 hospitals

$428

Corning, NY

3 hospitals

$452

Tucson, AZ

3 hospitals

$1,952

Spokane, WA

3 hospitals

$268

Madison, WI

3 hospitals

$1,615

Lubbock, TX

3 hospitals

$961

Knoxville, TN

3 hospitals

$544

Green Bay, WI

3 hospitals

$891

Eau Claire, WI

3 hospitals

$1,469

Akron, OH

3 hospitals

$410

San Antonio, TX

3 hospitals

$743

San Jose, CA

3 hospitals

$3,432

Oklahoma City, OK

3 hospitals

$632

Shreveport, LA

3 hospitals

$566

Waterloo, IA

3 hospitals

$671

Lowest published cash prices

1
Nocona General Hospital

Nocona, TX · file Feb 2026

$28
3
Doctors Center Hospital Carolina LLC

Carolina, PR · file date unknown

$75
4
$80
6
Bella Vista Hospital

Mayaguez, PR · file Mar 2026

$126
7
Erlanger Bledsoe Hospital

Pikeville, TN · file Jan 2026

$134
8
North Texas Medical Center

Gainesville, TX · compare in metro · file date unknown

$145
9
Wynn Hospital

Utica, NY · compare in metro · file Aug 2026

$148
10
Northwest Health-La Porte

La Porte, IN · compare in metro · file Apr 2026

$165
11
Arkansas Children's Hospital

Little Rock, AR · compare in metro · file Aug 2026

$170
12
Arkansas Children's Northwest, INC

Springdale, AR · compare in metro · file Aug 2026

$170
13
Kosciusko Community Hospital

Warsaw, IN · compare in metro · file Apr 2026

$174
14
$194
15
Nacogdoches Memorial Hospital

Nacogdoches, TX · compare in metro · file date unknown

$197

A colonoscopy is an examination of the large intestine with a flexible camera passed through the rectum. The diagnostic version, CPT 45378, is the base procedure: the doctor looks, and if nothing needs to be removed or sampled, this is the code the hospital bills. Most people are sedated and go home the same day.

What the price covers

The hospital's price for 45378 is the facility fee: the endoscopy suite, nursing, the scope and its cleaning, recovery time and disposable supplies. It usually does not include the gastroenterologist's professional fee, the anesthesia provider, or pathology if a sample is taken. Those are billed separately, often by different companies, and can add several hundred dollars to what you see here.

If polyps are found and removed, the code changes to 45385 (polyp removal) or 45380 (biopsy), and the price changes with it. A hospital's cash price for 45378 is the best starting point, not a guarantee of the final bill.

Screening versus diagnostic

A screening colonoscopy for someone with no symptoms is preventive care, which most insurance plans cover without cost-sharing. A diagnostic colonoscopy, done because of symptoms or a positive stool test, is not. The same procedure, the same room, a different code and a different bill. If you are insured, ask before the appointment which one will be billed.

Why prices vary so much

The spread between hospitals is often five to ten times for this code. Academic medical centers and large systems tend to list higher gross charges and higher negotiated rates; community hospitals and hospital-owned outpatient centers tend to be cheaper. Location matters less than ownership and system size. Freestanding ambulatory surgery centers, which are not in these files, are often cheaper still.

Questions to ask before you book

  • Is this the self-pay price for CPT 45378, in writing?
  • Does it include the physician, anesthesia and pathology, or are those separate?
  • If a polyp is removed, what does the price become?
  • Is there a prompt-pay or financial-assistance discount on top of the cash price?
1

What the number is

The hospital's discounted cash price for CPT 45378, facility part. Physician and anesthesia usually bill separately.

2

Cash vs. insured

With insurance you pay a share of the negotiated rate, which can be higher than the cash price. You may ask for the cash price instead.

3

What to say on the phone

"I'd like the self-pay price for CPT 45378, in writing, and whether it covers facility, physician and anesthesia."