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Colonoscopy (diagnostic) in Houston, TX costs $291 to $1,835. Here's every hospital's price.

11 hospitals in the Houston-Pasadena-The Woodlands, TX metro area publish a cash price for colonoscopy (diagnostic) (CPT 45378). We read their files every month so you don't have to.

Across the Houston-Pasadena-The Woodlands, TX metro area, 11 hospitals list a cash price for colonoscopy (diagnostic) (CPT 45378). The lowest is $291 at University of Texas Medical Branch Galveston, the median is $866 and the highest is $1,835 at Harris Health. The most expensive hospital lists 6.3 times the cheapest for the same code.

The Houston, TX median of $866 is 42% below the national median of $1,500 across 304 US hospitals with a cash price for this code.

16 of these hospitals also publish the rates they negotiated with insurers, from $82 to $9,865. With insurance you pay a share of the negotiated rate, which is sometimes higher than the cash price; you may ask for the cash price instead.

The files behind these prices are dated between March 2023 and April 2026. 44 other hospitals in the metro area have no readable price for this code: some publish no file, some block automated reading, some leave the code out. They are listed below so you can call them.

$291
lowest cash price in Houston, TX
University of Texas Medical Branch Galveston · 48 mi
$575 below the median
$866
median cash price
11 hospitals
6.3×
highest ÷ lowest
same procedure, same metro
11/60
hospitals with a cash price
44 don't · see who

Sorted by cash price

Hospital facility fee only
1
University of Texas Medical Branch Galveston

Galveston · 48 mi · Older file Mar 2023

$291
list $1,287 · lowest of 5 lines
2
Houston Methodist Hospital

Houston · 7 mi · File Apr 2026

$519
list $1,038 · lowest of 2 lines
3
Houston Methodist Baytown Hospital

Baytown · 22 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
4
Houston Methodist Clear Lake Hospital

Nassau Bay · 23 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
5
Houston Methodist Sugarland Hospital

Sugar Land · 24 mi · File Apr 2026

$866
list $1,732
6
Houston Methodist Willowbrook Hospital

Houston · 17 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
7
Houston Methodist West Hospital

Houston · 21 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
8
Houston Methodist the Woodlands Hospital

The Woodlands · 29 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
9
Houston Methodist Cypress Hospital

Cypress · 23 mi · File Apr 2026

$866
list $1,732 · lowest of 2 lines
10
St Luke's Patients Medical Center

Pasadena · 16 mi · File Feb 2026

$1,376
list $3,931 · lowest of 4 lines
11
Harris Health

Houston · 7 mi · File Mar 2026

$1,835
list $3,880 · lowest of 2 lines
12
Baylor St Lukes Medical Center

Houston · 7 mi · File Feb 2026

1

What's in the price

The hospital facility fee for CPT 45378. The doctor, anesthesia and lab work usually bill separately.

2

Cash vs. insured

Cash is what you pay without insurance. With insurance you pay a share of the negotiated rate, which can be higher than cash. You may ask for the cash price.

3

What to say on the phone

"I'd like the self-pay price for CPT 45378, in writing, and whether it covers facility, physician and anesthesia."

About colonoscopy (diagnostic)

A colonoscopy is an examination of the large intestine with a flexible camera passed through the rectum. The diagnostic version, CPT 45378, is the base procedure: the doctor looks, and if nothing needs to be removed or sampled, this is the code the hospital bills. Most people are sedated and go home the same day.

What the price covers

The hospital's price for 45378 is the facility fee: the endoscopy suite, nursing, the scope and its cleaning, recovery time and disposable supplies. It usually does not include the gastroenterologist's professional fee, the anesthesia provider, or pathology if a sample is taken. Those are billed separately, often by different companies, and can add several hundred dollars to what you see here.

If polyps are found and removed, the code changes to 45385 (polyp removal) or 45380 (biopsy), and the price changes with it. A hospital's cash price for 45378 is the best starting point, not a guarantee of the final bill.

Screening versus diagnostic

A screening colonoscopy for someone with no symptoms is preventive care, which most insurance plans cover without cost-sharing. A diagnostic colonoscopy, done because of symptoms or a positive stool test, is not. The same procedure, the same room, a different code and a different bill. If you are insured, ask before the appointment which one will be billed.

Why prices vary so much

The spread between hospitals is often five to ten times for this code. Academic medical centers and large systems tend to list higher gross charges and higher negotiated rates; community hospitals and hospital-owned outpatient centers tend to be cheaper. Location matters less than ownership and system size. Freestanding ambulatory surgery centers, which are not in these files, are often cheaper still.

Questions to ask before you book

  • Is this the self-pay price for CPT 45378, in writing?
  • Does it include the physician, anesthesia and pathology, or are those separate?
  • If a polyp is removed, what does the price become?
  • Is there a prompt-pay or financial-assistance discount on top of the cash price?

Hospitals in Houston, TX without a price for this procedure

Listed so you know who to call. The reason is what we found on their website.

Questions people ask