Colonoscopy (diagnostic) in Orlando, FL costs $2,483 to $3,344. Here's every hospital's price.
6 hospitals in the Orlando-Kissimmee-Sanford, FL metro area publish a cash price for colonoscopy (diagnostic) (CPT 45378). We read their files every month so you don't have to.
Across the Orlando-Kissimmee-Sanford, FL metro area, 6 hospitals list a cash price for colonoscopy (diagnostic) (CPT 45378). The lowest is $2,483 at UF Health Leesburg Hospital, the median is $2,996 and the highest is $3,344 at Orlando Health St Cloud Hospital.
The Orlando, FL median of $2,996 is 100% above the national median of $1,500 across 304 US hospitals with a cash price for this code.
7 of these hospitals also publish the rates they negotiated with insurers, from $637 to $9,679. With insurance you pay a share of the negotiated rate, which is sometimes higher than the cash price; you may ask for the cash price instead.
The files behind these prices are dated between March 2026 and April 2026. 7 other hospitals in the metro area have no readable price for this code: some publish no file, some block automated reading, some leave the code out. They are listed below so you can call them.
Sorted by cash price
Hospital facility fee onlyLeesburg · 40 mi · File Mar 2026
The Villages · 51 mi · File Mar 2026
Orlando · 10 mi · File Apr 2026
Ocoee · 13 mi · File Apr 2026
Clermont · 23 mi · File Apr 2026
Saint Cloud · 14 mi · File Apr 2026
What's in the price
The hospital facility fee for CPT 45378. The doctor, anesthesia and lab work usually bill separately.
Cash vs. insured
Cash is what you pay without insurance. With insurance you pay a share of the negotiated rate, which can be higher than cash. You may ask for the cash price.
What to say on the phone
"I'd like the self-pay price for CPT 45378, in writing, and whether it covers facility, physician and anesthesia."
About colonoscopy (diagnostic)
A colonoscopy is an examination of the large intestine with a flexible camera passed through the rectum. The diagnostic version, CPT 45378, is the base procedure: the doctor looks, and if nothing needs to be removed or sampled, this is the code the hospital bills. Most people are sedated and go home the same day.
What the price covers
The hospital's price for 45378 is the facility fee: the endoscopy suite, nursing, the scope and its cleaning, recovery time and disposable supplies. It usually does not include the gastroenterologist's professional fee, the anesthesia provider, or pathology if a sample is taken. Those are billed separately, often by different companies, and can add several hundred dollars to what you see here.
If polyps are found and removed, the code changes to 45385 (polyp removal) or 45380 (biopsy), and the price changes with it. A hospital's cash price for 45378 is the best starting point, not a guarantee of the final bill.
Screening versus diagnostic
A screening colonoscopy for someone with no symptoms is preventive care, which most insurance plans cover without cost-sharing. A diagnostic colonoscopy, done because of symptoms or a positive stool test, is not. The same procedure, the same room, a different code and a different bill. If you are insured, ask before the appointment which one will be billed.
Why prices vary so much
The spread between hospitals is often five to ten times for this code. Academic medical centers and large systems tend to list higher gross charges and higher negotiated rates; community hospitals and hospital-owned outpatient centers tend to be cheaper. Location matters less than ownership and system size. Freestanding ambulatory surgery centers, which are not in these files, are often cheaper still.
Questions to ask before you book
- Is this the self-pay price for CPT 45378, in writing?
- Does it include the physician, anesthesia and pathology, or are those separate?
- If a polyp is removed, what does the price become?
- Is there a prompt-pay or financial-assistance discount on top of the cash price?
Hospitals in Orlando, FL without a price for this procedure
Listed so you know who to call. The reason is what we found on their website.
- Central Florida Lake Monroe HospitalNo price file found
- HCA Florida Osceola HospitalNo price file found
- HCA Florida Poinciana HospitalNo price file found
- Nemours Childrens Hospital, Floridacode not in file
- Orlando HealthNo price file found
- Oviedo Medical CenterNo price file found
- UCF Lake Nona HospitalNo price file found