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Colonoscopy with polyp removal in St. Louis, MO-IL costs $1,391 to $5,032. Here's every hospital's price.

10 hospitals in the St. Louis, MO-IL metro area publish a cash price for colonoscopy with polyp removal (CPT 45385). We read their files every month so you don't have to.

Across the St. Louis, MO-IL metro area, 10 hospitals list a cash price for colonoscopy with polyp removal (CPT 45385). The lowest is $1,391 at Ssm St Joseph Health Center, the median is $1,391 and the highest is $5,032 at Mercy Hospital Jefferson. The most expensive hospital lists 3.6 times the cheapest for the same code.

The St. Louis, MO-IL median of $1,391 is 12% below the national median of $1,584 across 871 US hospitals with a cash price for this code.

12 of these hospitals also publish the rates they negotiated with insurers, from $212 to $5,680. With insurance you pay a share of the negotiated rate, which is sometimes higher than the cash price; you may ask for the cash price instead.

The files behind these prices are dated between March 2026 and June 2026. 21 other hospitals in the metro area have no readable price for this code: some publish no file, some block automated reading, some leave the code out. They are listed below so you can call them.

$1,391
lowest cash price in St. Louis, MO-IL
Ssm St Joseph Health Center · 8 mi
$1,391
median cash price
10 hospitals
3.6×
highest ÷ lowest
same procedure, same metro
10/36
hospitals with a cash price
21 don't · see who

Sorted by cash price

Hospital facility fee only
1
Ssm St Joseph Health Center

Saint Charles · 8 mi · File Apr 2026

$1,391
list $2,529 · lowest of 2 lines
2
Ssm St Clare Health Center

Fenton · 16 mi · File Apr 2026

$1,391
list $2,529 · lowest of 8 lines
3
Ssm Health St Mary's Hospital - St Louis

Saint Louis · 8 mi · File Apr 2026

$1,391
list $2,529
4
Ssm Health Depaul Hospital St Louis

Bridgeton · 5 mi · File Apr 2026

$1,391
list $2,529
5
Ssm St Joseph Hospital West

Lake Saint Louis · 24 mi · File Apr 2026

$1,391
list $2,529 · lowest of 15 lines
6
Mercy Hospital South

Saint Louis · 16 mi · File Jun 2026

$2,939
list $4,522 · lowest of 2 lines
7
Mercy Hospital St Louis

Saint Louis · 8 mi · File Jun 2026

$4,293
list $6,605
8
Mercy Hospital Washington

Washington · 38 mi · File Jun 2026

$4,412
list $6,788
9
Mercy Hospital Lincoln

Troy · 38 mi · File Jun 2026

$4,882
list $7,510
10
Mercy Hospital Jefferson

Crystal City · 38 mi · File Jun 2026

$5,032
list $7,741
11
OSF Saint Anthony's Health Center

Alton · 15 mi · File Mar 2026

—
12
Hshs Holy Family Hospital INC

Greenville · 52 mi · File Mar 2026

—
1

What's in the price

The hospital facility fee for CPT 45385. The doctor, anesthesia and lab work usually bill separately.

2

Cash vs. insured

Cash is what you pay without insurance. With insurance you pay a share of the negotiated rate, which can be higher than cash. You may ask for the cash price.

3

What to say on the phone

"I'd like the self-pay price for CPT 45385, in writing, and whether it covers facility, physician and anesthesia."

About colonoscopy with polyp removal

CPT 45385 is a colonoscopy in which a polyp is removed with a wire snare. It is the most common outcome for people over 50: about a third of colonoscopies find at least one polyp, and removing it during the same exam is the point of the procedure. You cannot book 45385 in advance; it is billed when a polyp is found.

What the price covers

The hospital's price is the facility fee for the endoscopy unit: room, nursing, sedation monitoring, the snare and other disposables, and recovery. Physician, anesthesia and pathology are separate bills. Every removed polyp goes to pathology, so with several polyps the pathology bill can rival the facility fee.

Cash price versus insured price

With insurance, a screening colonoscopy that turns into a polyp removal is still supposed to be covered as preventive under the Affordable Care Act rules, but billing errors are common. Without insurance, the cash price listed here is what to negotiate from. Some hospitals' cash price is lower than the rate they negotiated with insurers; you are allowed to ask for the cash price even if you are insured.

Why prices vary

Expect a wide spread within one metro area. It follows the hospital, not the procedure: the same snare, the same 30 minutes, priced according to what each system has decided its chargemaster should say. Hospital-owned outpatient centers and community hospitals are usually the low end.

Questions to ask

  • What is the self-pay price for 45385, and what for 45378 if no polyp is found?
  • How is pathology billed, per specimen or flat?
  • Is anesthesia by a nurse anesthetist or an anesthesiologist, and who bills it?

Hospitals in St. Louis, MO-IL without a price for this procedure

Listed so you know who to call. The reason is what we found on their website.

Questions people ask