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Colonoscopy with biopsy in Indianapolis, IN costs $333 to $3,717. Here's every hospital's price.

4 hospitals in the Indianapolis-Carmel-Greenwood, IN metro area publish a cash price for colonoscopy with biopsy (CPT 45380). We read their files every month so you don't have to.

Across the Indianapolis-Carmel-Greenwood, IN metro area, 4 hospitals list a cash price for colonoscopy with biopsy (CPT 45380). The lowest is $333 at Hendricks Regional Health, the median is $1,027 and the highest is $3,717 at Eskenazi Health. The most expensive hospital lists 11 times the cheapest for the same code.

The Indianapolis, IN median of $1,027 is 30% below the national median of $1,459 across 780 US hospitals with a cash price for this code.

10 of these hospitals also publish the rates they negotiated with insurers, from $167 to $3,667. With insurance you pay a share of the negotiated rate, which is sometimes higher than the cash price; you may ask for the cash price instead.

The files behind these prices are dated between January 2026 and May 2026. 16 other hospitals in the metro area have no readable price for this code: some publish no file, some block automated reading, some leave the code out. They are listed below so you can call them.

$333
lowest cash price in Indianapolis, IN
Hendricks Regional Health · 21 mi
$694 below the median
$1,027
median cash price
4 hospitals
11×
highest ÷ lowest
same procedure, same metro
4/26
hospitals with a cash price
16 don't · see who

Sorted by cash price

Hospital facility fee only
1
Hendricks Regional Health

Danville · 21 mi · File May 2026

$333
list $832
2
Witham Health Services

Lebanon · 25 mi · File Mar 2026

$1,027
list $1,467
3
Johnson Memorial Hospital

Franklin · 22 mi · File May 2026

$1,101
list $1,376
4
Eskenazi Health

Indianapolis · 3 mi · File Mar 2026

$3,717
list $4,130 · lowest of 2 lines
5
Ascension St Vincent Hospital

Indianapolis · 9 mi · File Jan 2026

6
Ascension St Vincent Anderson

Anderson · 32 mi · File Jan 2026

7
St Vincent Heart Center

Carmel · 10 mi · File Jan 2026

8
Ascension St Vincent Carmel

Carmel · 13 mi · File Jan 2026

9
Ascension St Vincent Fishers

Fishers · 15 mi · File Jan 2026

10
Ascension St Vincent Mercy

Elwood · 37 mi · File Jan 2026

1

What's in the price

The hospital facility fee for CPT 45380. The doctor, anesthesia and lab work usually bill separately.

2

Cash vs. insured

Cash is what you pay without insurance. With insurance you pay a share of the negotiated rate, which can be higher than cash. You may ask for the cash price.

3

What to say on the phone

"I'd like the self-pay price for CPT 45380, in writing, and whether it covers facility, physician and anesthesia."

About colonoscopy with biopsy

CPT 45380 is a colonoscopy during which the doctor takes one or more tissue samples for the laboratory. It starts as an ordinary colonoscopy; the biopsy is decided during the exam, so most patients are scheduled for a diagnostic or screening colonoscopy and end up with this code instead.

What the price covers

The hospital's number is the facility fee for the endoscopy suite, sedation nursing, recovery and supplies, including the biopsy forceps. The gastroenterologist, the anesthesia provider and the pathologist who reads the sample bill separately. Pathology alone commonly adds $100 to $400 per specimen, so ask how many samples are expected.

How this relates to the other colonoscopy codes

  • 45378: colonoscopy, nothing removed
  • 45380: colonoscopy with biopsy (this page)
  • 45385: colonoscopy with polyp removal by snare

A hospital's prices for the three usually sit close together, with biopsy and polyp removal slightly above the base code. If a hospital lists only one of them, use it as a guide for the others and confirm by phone.

Why prices vary

The range between hospitals in the same metro area is commonly several times. Ownership and size drive it more than geography: large systems and teaching hospitals list higher charges; community hospitals list lower ones. Cash prices are often far below the gross charge because most hospitals apply a fixed self-pay discount.

Questions to ask

  • What is the self-pay price for 45380, and does it include pathology?
  • Who bills for anesthesia, and what is their cash rate?
  • If no biopsy is needed after all, will you bill 45378 instead?

Hospitals in Indianapolis, IN without a price for this procedure

Listed so you know who to call. The reason is what we found on their website.

Questions people ask